The Rabbit Polyclonal anti-CLN5 antibody (ABIN7219404) specifically detects CLN5 in WB and ELISA.
The antibody is reactive with Human, Rat and Mouse samples.
CLN5
Reactivity: Human
WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Expiry Date
12 months
Target
CLN5
(Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))
Alternative Name
CLN5
Background
CLN5, Ceroid-lipofuscinosis neuronal protein 5, Protein CLN5CLN5 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.