CCL23 antibody (AA 40-120)

Catalog No. ABIN7227646

This Rabbit Polyclonal antibody specifically detects CCL23 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CCL23 antibody (AA 40-120) (ABIN7227646)

Target: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL23 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCL23 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-CCL23 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CCL23 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CCL23 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CCL23

Target: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Alternative Name: CCL23

Background: C-C motif chemokine 23, CK-beta-8, CKB-8, Macrophage inflammatory protein 3, MIP-3, Myeloid progenitor inhibitory factor 1, MPIF-1, Small-inducible cytokine A23CCL23 (C-C Motif Chemokine Ligand 23) is a Protein Coding gene. Among its related pathways are Akt Signaling and PEDF Induced Signaling. CCL23 is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of CCL23 is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

Molecular Weight: 13kD

Gene ID: 6368

UniProt: P55773