CCL26 antibody (Internal Region)

Catalog No. ABIN7217850

This Rabbit Polyclonal antibody specifically detects CCL26 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for CCL26 antibody (Internal Region) (ABIN7217850)

Target: CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL26 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CCL26 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Eotaxin-3 Polyclonal Antibody

Specificity: Eotaxin-3 Polyclonal Antibody detects endogenous levels of Eotaxin-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Eotaxin-3

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CCL26

Target: CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))

Alternative Name: Eotaxin-3

Background: CCL26, SCYA26, C-C motif chemokine 26, CC chemokine IMAC, Eotaxin-3, Macrophage inflammatory protein 4-alpha, MIP-4-alpha, Small-inducible cytokine A26, Thymic stroma chemokine-1, TSC-1CCL26 is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases.

Molecular Weight: 12kD

Gene ID: 10344

UniProt: Q9Y258

Pathways: Regulation of Actin Filament Polymerization