FDCSP antibody (C-Term)

Catalog No. ABIN7220950

This Rabbit Polyclonal antibody specifically detects FDCSP in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for FDCSP antibody (C-Term) (ABIN7220950)

Target: FDCSP (C4orf7) (Chromosome 4 Open Reading Frame 7 (C4orf7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FDCSP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FDCSP Antibody

Binding Specificity: C-Term

Purpose: Rabbit Anti-FDC-SP Polyclonal Antibody

Specificity: FDC-SP Polyclonal Antibody detects endogenous levels of FDC-SP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human FDC-SP

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FDCSP

Target: FDCSP (C4orf7) (Chromosome 4 Open Reading Frame 7 (C4orf7))

Alternative Name: FDC-SP

Background: FDCSP, C4orf7, Follicular dendritic cell secreted peptide, FDC secreted protein, FDC-SPFDCSP encodes a small secreted protein that is expressed in follicular dendritic cells. Follicular dendritic cell secreted peptide specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion. an bind to the surface of B-lymphoma cells, but not T-lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

Gene ID: 260436

UniProt: Q8NFU4