F2RL3 antibody (AA 260-340)

Catalog No. ABIN7216446

This Rabbit Polyclonal antibody specifically detects F2RL3 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for F2RL3 antibody (AA 260-340) (ABIN7216446)

Target: F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F2RL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-F2RL3 Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-PAR4 Polyclonal Antibody

Specificity: PAR4 Polyclonal Antibody detects endogenous levels of PAR4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human PAR4 at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for F2RL3

Target: F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))

Alternative Name: PAR4

Background: PAWR, PAR4, PRKC apoptosis WT1 regulator protein, Prostate apoptosis response 4 protein, Par-4The tumor suppressor WT1 represses and activates transcription. Pro-apoptotic WT1 regulator encoded by PAWR is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. Pro-apoptotic WT1 regulator is specifically upregulated during apoptosis of prostate cells.

Molecular Weight: 36kD

Gene ID: 5074

UniProt: Q96IZ0

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process