C1QL3 antibody

Catalog No. ABIN7227542

The Rabbit Polyclonal anti-C1QL3 antibody (ABIN7227542) specifically detects C1QL3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for C1QL3 antibody (ABIN7227542)

Target: C1QL3 (Complement Component 1, Q Subcomponent-Like 3 (C1QL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-C1QL3 Antibody

Purpose: Rabbit Anti-C1QL3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of C1QL3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human C1QL3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for C1QL3

Target: C1QL3 (Complement Component 1, Q Subcomponent-Like 3 (C1QL3))

Alternative Name: C1QL3

Background: Complement C1q-like protein 3, C1q and tumor necrosis factor-related protein 13, C1q/TNF-related protein 13C1QL3 (Complement C1q Like 3) is a Protein Coding gene. An important paralog of this gene is C1QL1. May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production (By similarity).

Molecular Weight: 28kD

Gene ID: 389941

UniProt: Q5VWW1