CFHR1 antibody

Catalog No. ABIN7228530

This Rabbit Polyclonal antibody specifically detects CFHR1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CFHR1 antibody (ABIN7228530)

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CFHR1 Antibody

Purpose: Rabbit Anti-FHR1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FHR1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FHR1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CFHR1

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Alternative Name: FHR1

Background: Complement factor H-related protein 1, FHR-1, H factor-like protein 1, H-factor-like 1, H36CFHR1 encodes Complement Factor H Related 1 belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Molecular Weight: 36kD

Gene ID: 3078

UniProt: Q03591