CNTNAP1 antibody

Catalog No. ABIN7227990

This Rabbit Polyclonal antibody specifically detects CNTNAP1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for CNTNAP1 antibody (ABIN7227990)

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNTNAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CNTNAP1 Antibody

Purpose: Rabbit Anti-CNTP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CNTP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CNTP1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CNTNAP1

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Alternative Name: CNTP1

Background: Contactin-associated protein 1, Caspr, Caspr1, Neurexin IV, Neurexin-4, p190CNTNAP1 product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for contactin-associated protein, includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Molecular Weight: 152kD

Gene ID: 8506

UniProt: P78357

Pathways: Cell-Cell Junction Organization