Cyclin I antibody (AA 30-110)

Catalog No. ABIN7227660

The Rabbit Polyclonal anti-Cyclin I antibody is suitable to detect Cyclin I in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for Cyclin I antibody (AA 30-110) (ABIN7227660)

Target: Cyclin I (CCNI)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin I antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cyclin I Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-CCNI Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CCNI protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CCNI protein at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cyclin I

Target: Cyclin I (CCNI)

Alternative Name: CCNI

Background: Cyclin-IThe protein encoded by CCNI (Cyclin I) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of CCNI was found to be expressed constantly during cell cycle progression. CCNI is a Protein Coding gene. Diseases associated with CCNI include Epilepsy, Familial Temporal Lobe, 3. An important paralog of CCNI is CCNI2.

Molecular Weight: 41kD

Gene ID: 10983

UniProt: Q14094

Pathways: Cell Division Cycle