CDKN3 antibody (AA 1-80)

Catalog No. ABIN7218970

The Rabbit Polyclonal anti-CDKN3 antibody is suitable to detect CDKN3 in samples from Human and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for CDKN3 antibody (AA 1-80) (ABIN7218970)

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CDKN3 Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-CDKN3 Polyclonal Antibody

Specificity: CDKN3 Polyclonal Antibody detects endogenous levels of CDKN3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CDKN3 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDKN3

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Alternative Name: CDKN3

Background: CDKN3, CDI1, CIP2, KAP, Cyclin-dependent kinase inhibitor 3, CDK2-associated dual-specificity phosphatase, Cyclin-dependent kinase interactor 1, Cyclin-dependent kinase-interacting protein 2, Kinase-associated phosphataseThe cyclin dependent kinase inhibitor 3 encoded by CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. CDKN3 was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 23kD

Gene ID: 1033

UniProt: Q16667