COX6C antibody (AA 30-110)

Catalog No. ABIN7214308

The Rabbit Polyclonal anti-COX6C antibody (ABIN7214308) specifically detects COX6C in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for COX6C antibody (AA 30-110) (ABIN7214308)

Target: COX6C (Cytochrome C Oxidase Subunit VIc (COX6C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX6C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-COX6C Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-COX6c Polyclonal Antibody

Specificity: COX6c Polyclonal Antibody detects endogenous levels of COX6c protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human COX6c at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for COX6C

Target: COX6C (Cytochrome C Oxidase Subunit VIc (COX6C))

Alternative Name: COX6c

Background: COX6C, Cytochrome c oxidase subunit 6C, Cytochrome c oxidase polypeptide VIcCytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77 % amino acid sequence identity with mouse subunit VIc. COX6C is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.

Molecular Weight: 32kD

Gene ID: 1345

UniProt: P09669

Pathways: Proton Transport