CRLF3 antibody (AA 270-350)

Catalog No. ABIN7228062

The Rabbit Polyclonal anti-CRLF3 antibody (ABIN7228062) specifically detects CRLF3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for CRLF3 antibody (AA 270-350) (ABIN7228062)

Target: CRLF3 (Cytokine Receptor-Like Factor 3 (CRLF3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CRLF3 Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-CRLF3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CRLF3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CRLF3 protein at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CRLF3

Target: CRLF3 (Cytokine Receptor-Like Factor 3 (CRLF3))

Alternative Name: CRLF3

Background: Cytokine receptor-like molecule 9, CREME-9, Cytokine receptor-related protein 4, Type I cytokine receptor-like factor p48CRLF3 (Cytokine Receptor Like Factor 3) is a Protein Coding gene. CRLF3 encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. CRLF3 is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing ofCRLF3 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.

Molecular Weight: 48kD

Gene ID: 51379

UniProt: Q8IUI8

Pathways: p53 Signaling