DFNA5 antibody (AA 200-280)

Catalog No. ABIN7217644

This Rabbit Polyclonal antibody specifically detects DFNA5 in WB and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for DFNA5 antibody (AA 200-280) (ABIN7217644)

Target: DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DFNA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DFNA5 Antibody

Binding Specificity: AA 200-280

Purpose: Rabbit Anti-DFNA5 Polyclonal Antibody

Specificity: DFNA5 Polyclonal Antibody detects endogenous levels of DFNA5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human DFNA5 at AA range: 200-280

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DFNA5

Target: DFNA5 (Deafness, Autosomal Dominant 5 (DFNA5))

Alternative Name: DFNA5

Background: DFNA5, ICERE1, Non-syndromic hearing impairment protein 5, Inversely correlated with estrogen receptor expression 1, ICERE-1Hearing impairment is a heterogeneous condition with over 40 loci described. Non-syndromic hearing impairment protein 5 encoded by DFNA5 is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight: 54kD

Gene ID: 1687

UniProt: O60443

Pathways: Sensory Perception of Sound