DHRS9 antibody

Catalog No. ABIN7228210

The Rabbit Polyclonal anti-DHRS9 antibody (ABIN7228210) specifically detects DHRS9 in ELISA and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DHRS9 antibody (ABIN7228210)

Target: DHRS9 (Dehydrogenase/reductase (SDR Family) Member 9 (DHRS9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHRS9 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-DHRS9 Antibody

Purpose: Rabbit Anti-DHRS9 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DHRS9 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DHRS9 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DHRS9

Target: DHRS9 (Dehydrogenase/reductase (SDR Family) Member 9 (DHRS9))

Alternative Name: DHRS9

Background: Dehydrogenase/reductase SDR family member 9, 3-alpha hydroxysteroid dehydrogenase, 3-alpha-HSD, NADP-dependent retinol dehydrogenase/reductase, RDH-E2, RDHL, Retinol dehydrogenase 15, Short chain dehydrogenase/reductase family 9C member 4, Short-chain dehydrogenase/reductase retSDR8, Tracheobronchial epithelial cell-specific retinol dehydrogenase, RDH-TBEDHRS9 (Dehydrogenase/Reductase 9) is a Protein Coding gene. Among its related pathways are the visual cycle I (vertebrates) and Drug metabolism - cytochrome P450. DHRS9 encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants.

Molecular Weight: 35kD

Gene ID: 10170

UniProt: Q9BPW9

Pathways: C21-Steroid Hormone Metabolic Process