DLL3 antibody (AA 510-590)

Catalog No. ABIN7228240

The Rabbit Polyclonal anti-DLL3 antibody is suitable to detect DLL3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for DLL3 antibody (AA 510-590) (ABIN7228240)

Target: DLL3 (delta Like Protein 3 (DLL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DLL3 Antibody

Binding Specificity: AA 510-590

Purpose: Rabbit Anti-DLL3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DLL3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DLL3 protein at AA range: 510-590

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DLL3

Target: DLL3 (delta Like Protein 3 (DLL3))

Alternative Name: DLL3

Background: Delta-like protein 3, Drosophila Delta homolog 3, Delta3DLL3 encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in DLL3 cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for DLL3.

Molecular Weight: 67kD

Gene ID: 10683

UniProt: Q9NYJ7

Pathways: Notch Signaling