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Desmin antibody (pSer60)

The Rabbit Polyclonal anti-Desmin antibody is suitable to detect Desmin in samples from Human, Rat and Mouse. It has been validated for IHC, ELISA and IF.
Catalog No. ABIN7220022
$315.92
Plus shipping costs $50.00
Shipping to: United States
Delivery in 12 to 16 Business Days

Quick Overview for Desmin antibody (pSer60) (ABIN7220022)

Target

See all Desmin (DES) Antibodies
Desmin (DES)

Reactivity

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Human, Rat, Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Desmin antibody is un-conjugated

Application

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • Binding Specificity

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    pSer60

    Purpose

    Rabbit Anti-Desmin (phospho Ser60) Polyclonal Antibody

    Specificity

    Phospho-Desmin (S60) Polyclonal Antibody detects endogenous levels of Desmin protein only when phosphorylated at S60.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Immunogen

    Synthesized peptide derived from human Desmin Phospho-Ser60

    Isotype

    IgG
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    Expiry Date

    12 months
  • Target

    Desmin (DES)

    Alternative Name

    Desmin

    Background

    DES, DesminDES encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

    Gene ID

    1674

    UniProt

    P17661
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