DRAM antibody (AA 151-200)

Catalog No. ABIN7228294

The Rabbit Polyclonal anti-DRAM antibody is suitable to detect DRAM in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for DRAM antibody (AA 151-200) (ABIN7228294)

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRAM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DRAM Antibody

Binding Specificity: AA 151-200

Purpose: Rabbit Anti-DRAM1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DRAM1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DRAM1 protein at AA range: 151-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DRAM

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Alternative Name: DRAM1

Background: DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulatorDRAM1 is regulated as part of the p53 tumor suppressor pathway. DRAM1 encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of DRAM1 is associated with various tumors. This gene has a pseudogene on chromosome 4.

Molecular Weight: 26kD

Gene ID: 55332

UniProt: Q8N682