DCLK3 antibody (AA 260-340)

Catalog No. ABIN7214528

This Rabbit Polyclonal antibody specifically detects DCLK3 in ELISA, IHC, WB and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for DCLK3 antibody (AA 260-340) (ABIN7214528)

Target: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCLK3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-DCLK3 Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-DCAMKL3 Polyclonal Antibody

Specificity: DCAMKL3 Polyclonal Antibody detects endogenous levels of DCAMKL3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human DCAMKL3 at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DCLK3

Target: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Alternative Name: DCAMKL3

Background: DCLK3, DCAMKL3, DCDC3C, KIAA1765, Serine/threonine-protein kinase DCLK3, Doublecortin domain-containing protein 3C, Doublecortin-like and CAM kinase-like 3, Doublecortin-like kinase 3The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. DCAMKL3 (doublecortin-like and CAM kinase-like 3), also known as DCLK3 or DCDC3C, is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain. One of several members of the Ser/Thr protein kinase family, DCAMKL3 functions to catalyze the ATP-dependent attachment of a phospho residue to target proteins, an event that may play a role in various cellular processes.

Molecular Weight: 73kD

Gene ID: 85443

UniProt: Q9C098