DYRK1B antibody (AA 300-380)

Catalog No. ABIN7225842

The Rabbit Polyclonal anti-DYRK1B antibody (ABIN7225842) specifically detects DYRK1B in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for DYRK1B antibody (AA 300-380) (ABIN7225842)

Target: DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYRK1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-DYRK1B Antibody

Binding Specificity: AA 300-380

Purpose: Rabbit Anti-Dyrk1B Polyclonal Antibody

Specificity: Dyrk1B Polyclonal Antibody detects endogenous levels of Dyrk1B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Dyrk1B at AA range: 300-380

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DYRK1B

Target: DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))

Alternative Name: Dyrk1B

Background: DYRK1B, MIRK, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Minibrain-related kinase, Mirk protein kinaseDYRK1B (dual specificity tyrosine phosphorylation regulated kinase 1B) encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of DYRK1B may be altered in tumor cells, and mutations in DYRK1B were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants.

Molecular Weight: 70kD

Gene ID: 9149

UniProt: Q9Y463