DARC antibody (AA 10-90)

Catalog No. ABIN7220856

The Rabbit Polyclonal anti-DARC antibody is suitable to detect DARC in samples from Human and Mouse. It has been validated for ELISA and IF.

Quick Overview for DARC antibody (AA 10-90) (ABIN7220856)

Target: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DARC antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-DARC Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-Duffy Polyclonal Antibody

Specificity: Duffy Polyclonal Antibody detects endogenous levels of Duffy protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Duffy at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DARC

Target: DARC (Duffy Blood Group, Chemokine Receptor (DARC))

Alternative Name: Duffy

Background: DARC, FY, GPD, Duffy antigen/chemokine receptor, Fy glycoprotein, GpFy, Glycoprotein D, Plasmodium vivax receptor, CD antigen CD234The atypical chemokine receptor 1 (Duffy blood group) encoded by ACKR1 is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID: 2532

UniProt: Q16570