MARH8 antibody

Catalog No. ABIN8121113

This Rabbit Polyclonal antibody specifically detects MARH8 in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MARH8 antibody (ABIN8121113)

Target: MARH8 (e3 Ubiquitin-Protein Ligase 8-Mar (MARH8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARH8 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MARH8 Antibody

Purpose: MARH8 Antibody

Specificity: MARH8 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MARH8

Target: MARH8 (e3 Ubiquitin-Protein Ligase 8-Mar (MARH8))

Alternative Name: MARH8

Background:

Background: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153], Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010],

Gene Name: MARCH8 MIR RNF178

Protein Name: E3 ubiquitin-protein ligase MARCH8 (EC 6.3.2.-) (Cellular modulator of immune recognition) (c-MIR) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII) (RING finger protein 178)

Gene ID: 220972

UniProt: Q5T0T0