Ephrin A1 antibody (AA 40-120)

Catalog No. ABIN7214768

The Rabbit Polyclonal anti-Ephrin A1 antibody (ABIN7214768) specifically detects Ephrin A1 in ELISA, WB, IHC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Ephrin A1 antibody (AA 40-120) (ABIN7214768)

Target: Ephrin A1 (EFNA1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin A1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Ephrin A1 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-Ephrin-A1 Polyclonal Antibody

Specificity: Ephrin-A1 Polyclonal Antibody detects endogenous levels of Ephrin-A1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Ephrin-A1 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Ephrin A1

Target: Ephrin A1 (EFNA1)

Alternative Name: Ephrin-A1

Background: EFNA1, EPLG1, LERK1, TNFAIP4, Ephrin-A1, EPH-related receptor tyrosine kinase ligand 1, LERK-1, Immediate early response protein B61, Tumor necrosis factor alpha-induced protein 4, TNF alpha-induced protein 4EFNA1 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.

Molecular Weight: 24kD

Gene ID: 1942

UniProt: P20827

Pathways: RTK Signaling