Ephrin A5 antibody (AA 130-210)

Catalog No. ABIN7212510

The Rabbit Polyclonal anti-Ephrin A5 antibody has been validated for ELISA and WB. It is suitable to detect Ephrin A5 in samples from Human, Rat and Mouse.

Quick Overview for Ephrin A5 antibody (AA 130-210) (ABIN7212510)

Target: Ephrin A5 (EFNA5)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin A5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Ephrin A5 Antibody

Binding Specificity: AA 130-210

Purpose: Ephrin-A5 Polyclonal Antibody

Specificity: Ephrin-A5 Polyclonal Antibody detects endogenous levels of Ephrin-A5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Ephrin-A5 at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Ephrin A5

Target: Ephrin A5 (EFNA5)

Alternative Name: Ephrin-A5

Background: Rabbit Anti-Ephrin-A5 Polyclonal Antibody,EFNA5, EPLG7, LERK7, Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, LERK-7,Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.,Ephrin-A5

Molecular Weight: observerd band 26kDa

Gene ID: 1946

UniProt: P52803

Pathways: RTK Signaling