Ephrin B2 antibody (AA 210-290)

Catalog No. ABIN7228364

This Rabbit Polyclonal antibody specifically detects Ephrin B2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Ephrin B2 antibody (AA 210-290) (ABIN7228364)

Target: Ephrin B2 (EFNB2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Ephrin B2 Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-EFNB2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of EFNB2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human EFNB2 protein at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Ephrin B2

Target: Ephrin B2 (EFNB2)

Alternative Name: EFNB2

Background: Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5, HTK ligand, HTK-LEFNB2 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. EFNB2 encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.

Molecular Weight: 36kD

Gene ID: 1948

UniProt: P52799

Pathways: RTK Signaling, Regulation of Muscle Cell Differentiation