ERBB2IP antibody (pTyr1104)

Catalog No. ABIN7212952

This anti-ERBB2IP antibody is a Rabbit Polyclonal antibody detecting ERBB2IP in WB and ELISA. Suitable for Human.

Quick Overview for ERBB2IP antibody (pTyr1104) (ABIN7212952)

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB2IP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ERBB2IP Antibody

Binding Specificity: pTyr1104

Purpose: Erbin (phospho Tyr1104) Polyclonal Antibody

Specificity: Phospho-Erbin (Y1104) Polyclonal Antibody detects endogenous levels of Erbin protein only when phosphorylated at Y1104.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Erbin Phospho-Tyr1104

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ERBB2IP

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Alternative Name: Erbin

Background: Rabbit Anti-Erbin (phospho Tyr1104) Polyclonal Antibody,ERBB2IP, ERBIN, KIAA1225, LAP2, Protein LAP2, Densin-180-like protein, Erbb2-interacting protein, Erbin,ERBIN is a member of the leucine-rich repeat and PDZ domain (LAP) family.Erbb2 interacting protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ERBIN.,Protein LAP2

Molecular Weight: observerd band 172kDa

Gene ID: 55914

UniProt: Q96RT1

Pathways: EGFR Signaling Pathway, Asymmetric Protein Localization