Exonuclease 1 antibody (AA 30-110)

Catalog No. ABIN7214830

The Rabbit Polyclonal anti-Exonuclease 1 antibody is suitable to detect Exonuclease 1 in samples from Human and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for Exonuclease 1 antibody (AA 30-110) (ABIN7214830)

Target: Exonuclease 1 (EXO1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Exonuclease 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Exonuclease 1 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-Exo1 Polyclonal Antibody

Specificity: Exo1 Polyclonal Antibody detects endogenous levels of Exo1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Exo1 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Exonuclease 1

Target: Exonuclease 1 (EXO1)

Alternative Name: Exo1

Background: EXO1, EXOI, HEX1, Exonuclease 1, hExo1, Exonuclease I, hExoIEXO1 encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of EXO1 results in three transcript variants encoding two different isoforms.

Molecular Weight: 94kD

Gene ID: 9156

UniProt: Q9UQ84

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response