Fibrinogen beta Chain antibody (Internal Region)

Catalog No. ABIN7220510

This Rabbit Polyclonal antibody specifically detects Fibrinogen beta Chain in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Fibrinogen beta Chain antibody (Internal Region) (ABIN7220510)

Target: Fibrinogen beta Chain (FGB)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrinogen beta Chain antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Fibrinogen beta Chain Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Fibrinogen β Polyclonal Antibody

Specificity: Fibrinogen β Polyclonal Antibody detects endogenous levels of Fibrinogen β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Fibrinogen beta

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Alternative Name: Fibrinogen beta

Background: FGB, Fibrinogen beta chainThe fibrinogen beta chain encoded by FGB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 55kD

Gene ID: 2244

UniProt: P02675