FOXN1 antibody (AA 340-420)

Catalog No. ABIN7228580

The Rabbit Polyclonal anti-FOXN1 antibody is suitable to detect FOXN1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for FOXN1 antibody (AA 340-420) (ABIN7228580)

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOXN1 Antibody

Binding Specificity: AA 340-420

Purpose: Rabbit Anti-FOXN1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FOXN1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FOXN1 protein at AA range: 340-420

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FOXN1

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Alternative Name: FOXN1

Background: Forkhead box protein N1, Winged-helix transcription factor nudeMutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. FOXN1 is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in FOXN1 has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.

Molecular Weight: 71kD

Gene ID: 8456

UniProt: O15353