FPR2 antibody (AA 130-210)

Catalog No. ABIN7228588

The Rabbit Polyclonal anti-FPR2 antibody is suitable to detect FPR2 in samples from Human, Mouse, Rat and Pig. It has been validated for WB and ELISA.

Quick Overview for FPR2 antibody (AA 130-210) (ABIN7228588)

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FPR2 Antibody

Binding Specificity: AA 130-210

Purpose: Rabbit Anti-FPR2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FPR2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FPR2 protein at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FPR2

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Alternative Name: FPR2

Background: N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, HM63, Lipoxin A4 receptor, LXA4 receptor, RFPFPR2 (Formyl Peptide Receptor 2) is a Protein Coding gene. Diseases associated with FPR2 include Prion Disease. Among its related pathways are Akt Signaling and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and N-formyl peptide receptor activity. An important paralog of this gene is FPR3. Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Molecular Weight: 38kD

Gene ID: 2358

UniProt: P25090