FZD3 antibody (AA 110-190)

Catalog No. ABIN7214954

The Rabbit Polyclonal anti-FZD3 antibody (ABIN7214954) specifically detects FZD3 in WB, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for FZD3 antibody (AA 110-190) (ABIN7214954)

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-FZD3 Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-Frizzled-3 Polyclonal Antibody

Specificity: Frizzled-3 Polyclonal Antibody detects endogenous levels of Frizzled-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Frizzled-3 at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FZD3

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Alternative Name: Frizzled-3

Background: FZD3, Frizzled-3, Fz-3, hFz3FZD3 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of Frizzled-3 is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. FZD3 is a susceptibility locus for schizophrenia.

Molecular Weight: 76kD

Gene ID: 7976

UniProt: Q9NPG1

Pathways: WNT Signaling, Tube Formation