FZD4 antibody (AA 11-60)

Catalog No. ABIN7228592

This Rabbit Polyclonal antibody specifically detects FZD4 in ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FZD4 antibody (AA 11-60) (ABIN7228592)

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FZD4 Antibody

Binding Specificity: AA 11-60

Purpose: Rabbit Anti-Frizzled-4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of Frizzled-4

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Frizzled-4 protein at AA range: 11-60

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FZD4

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Alternative Name: Frizzled-4

Background: Frizzled-4, Fz-4, hFz4, FzE4, CD antigen CD344FZD4 (Frizzled Class Receptor 4) is a Protein Coding gene. Diseases associated with FZD4 include Exudative Vitreoretinopathy 1 and Exudative Vitreoretinopathy. Among its related pathways are Transcription Androgen Receptor nuclear signaling and phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex.

Gene ID: 8322

UniProt: Q9ULV1

Pathways: WNT Signaling, Hormone Transport, Sensory Perception of Sound