FRZB antibody (AA 150-230)

Catalog No. ABIN7231326

This Rabbit Polyclonal antibody specifically detects FRZB in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for FRZB antibody (AA 150-230) (ABIN7231326)

Target: FRZB (Frizzled-Related Protein (FRZB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRZB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FRZB Antibody

Binding Specificity: AA 150-230

Purpose: Rabbit Anti-SFRP3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SFRP3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SFRP3 protein at AA range: 150-230

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FRZB

Target: FRZB (Frizzled-Related Protein (FRZB))

Alternative Name: SFRP3

Background: Secreted frizzled-related protein 3, sFRP-3, Frezzled, Fritz, Frizzled-related protein 1, FrzB-1FRZB (Frizzled-Related Protein) is a Protein Coding gene. Diseases associated with FRZB include Osteoarthritis 1 and Osteoarthritis. Among its related pathways are Adipogenesis and Endochondral Ossification. The protein encoded by FRZB is a secreted protein that is involved in the regulation of bone development. Defects in FRZB are a cause of female-specific osteoarthritis (OA) susceptibility.

Molecular Weight: 35kD

Gene ID: 2487

UniProt: Q92765

Pathways: WNT Signaling, Positive Regulation of fat Cell Differentiation