GNG5 antibody (AA 10-90)

Catalog No. ABIN7221164

The Rabbit Polyclonal anti-GNG5 antibody (ABIN7221164) specifically detects GNG5 in ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GNG5 antibody (AA 10-90) (ABIN7221164)

Target: GNG5 (G Protein gamma 5 (GNG5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNG5 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-GNG5 Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-Gγ 5 Polyclonal Antibody

Specificity: Gγ 5 Polyclonal Antibody detects endogenous levels of Gγ 5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Ggamma 5 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GNG5

Target: GNG5 (G Protein gamma 5 (GNG5))

Alternative Name: Ggamma 5

Background: GNG5, GNGT5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327], summary by Ahmad et al. 1995) [PubMed 7606925].

Gene ID: 2787

UniProt: P63218

Pathways: Myometrial Relaxation and Contraction, SARS-CoV-2 Protein Interactome