GLB1 antibody (Internal Region)

Catalog No. ABIN7226732

The Rabbit Polyclonal anti-GLB1 antibody is suitable to detect GLB1 in samples from Human and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for GLB1 antibody (Internal Region) (ABIN7226732)

Target: GLB1 (Galactosidase, beta 1 (GLB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-GLB1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Galactosidase β Polyclonal Antibody

Specificity: Galactosidase β Polyclonal Antibody detects endogenous levels of Galactosidase β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Galactosidase beta

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GLB1

Target: GLB1 (Galactosidase, beta 1 (GLB1))

Alternative Name: Galactosidase beta

Background: GLB1, ELNR1, Beta-galactosidase, Acid beta-galactosidase, Lactase, Elastin receptor 1GLB1 (galactosidase beta 1) encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in GLB1 may result in GM1-gangliosidosis and Morquio B syndrome.

Molecular Weight: 76kD

Gene ID: 2720

UniProt: P16278

Pathways: Glycosaminoglycan Metabolic Process