The Rabbit Polyclonal anti-Galectin 3 antibody is suitable to detect Galectin 3 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.
LGALS3
Reactivity: Human
WB, IHC, ELISA, IF, IP
Host: Rabbit
Monoclonal
4E1
unconjugated
Recombinant Antibody
Application Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Expiry Date
12 months
Target
Galectin 3 (LGALS3)
Alternative Name
CBP 35
Target Type
Chemical
Background
LGALS3, MAC2, Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigenLGALS3 encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. lectin, galactoside binding soluble 3 is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. lectin, galactoside binding soluble 3 can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. lectin, galactoside binding soluble 3 localizes to the extracellular matrix, the cytoplasm and the nucleus. lectin, galactoside binding soluble 3 plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. lectin, galactoside binding soluble 3 exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.