GABRB1 antibody

Catalog No. ABIN7220886

The Rabbit Polyclonal anti-GABRB1 antibody (ABIN7220886) specifically detects GABRB1 in ELISA and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GABRB1 antibody (ABIN7220886)

Target: GABRB1 (gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GABRB1 Antibody

Purpose: GABAA Rβ1 Polyclonal Antibody

Specificity: GABAA Rβ1 Polyclonal Antibody detects endogenous levels of GABAA Rβ1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human GABAA range: Rbeta1 around the non-phosphorylation site of S434

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GABRB1

Target: GABRB1 (gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))

Alternative Name: GABAA Rbeta1

Background: Rabbit Anti-GABAA Rβ1 Polyclonal Antibody,GABRB1, Gamma-aminobutyric acid receptor subunit beta-1, GABA(A) receptor subunit beta-1,The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. GABRB1 encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of GABRB1 is implicated in the pathogenetics of schizophrenia.,Gamma-aminobutyric acid receptor subunit beta-1

Molecular Weight: observerd band 55kDa

Gene ID: 2560

UniProt: P18505