GDI1 antibody (C-Term)

Catalog No. ABIN7217620

The Rabbit Polyclonal anti-GDI1 antibody is suitable to detect GDI1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for GDI1 antibody (C-Term) (ABIN7217620)

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GDI1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit Anti-GDI-1 Polyclonal Antibody

Specificity: GDI-1 Polyclonal Antibody detects endogenous levels of GDI-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human GDI-1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GDI1

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Alternative Name: GDI-1

Background: GDI1, GDIL, OPHN2, RABGDIA, XAP4, Rab GDP dissociation inhibitor alpha, Rab GDI alpha, Guanosine diphosphate dissociation inhibitor 1, GDI-1, Oligophrenin-2, Protein XAP-4GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.

Molecular Weight: 50kD

Gene ID: 2664

UniProt: P31150