GANAB antibody (AA 220-300)

Catalog No. ABIN7220662

The Rabbit Polyclonal anti-GANAB antibody (ABIN7220662) specifically detects GANAB in WB, IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for GANAB antibody (AA 220-300) (ABIN7220662)

Target: GANAB (Glucosidase, Alpha, Neutral AB (GANAB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GANAB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-GANAB Antibody

Binding Specificity: AA 220-300

Purpose: Rabbit Anti-Glucosidase IIα Polyclonal Antibody

Specificity: Glucosidase IIα Polyclonal Antibody detects endogenous levels of Glucosidase IIα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Glucosidase IIalpha at AA range: 220-300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GANAB

Target: GANAB (Glucosidase, Alpha, Neutral AB (GANAB))

Alternative Name: Glucosidase IIalpha

Background: GANAB, G2AN, KIAA0088, Neutral alpha-glucosidase AB, Alpha-glucosidase 2, Glucosidase II subunit alphaGANAB encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.

Molecular Weight: 107kD

Gene ID: 23193

UniProt: Q14697