GDF2 antibody (AA 371-420)

Catalog No. ABIN7227494

This Rabbit Polyclonal antibody specifically detects GDF2 in ELISA and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for GDF2 antibody (AA 371-420) (ABIN7227494)

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GDF2 Antibody

Binding Specificity: AA 371-420

Purpose: BMP-9 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of BMP-9

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human BMP-9 protein at AA range: 371-420

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GDF2

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Alternative Name: BMP-9

Background: Rabbit Anti-BMP-9 Polyclonal Antibody,Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9,GDF2 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in GDF2 are associated with hereditary hemorrhagic telangiectasia.,BMP-9

Gene ID: 2658

UniProt: Q9UK05

Pathways: Transition Metal Ion Homeostasis