HMGA1 antibody

Catalog No. ABIN7228938

The Rabbit Polyclonal anti-HMGA1 antibody is suitable to detect HMGA1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for HMGA1 antibody (ABIN7228938)

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HMGA1 Antibody

Purpose: Rabbit Anti-HMGA1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HMGA1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HMGA1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HMGA1

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Alternative Name: HMGA1

Background: High mobility group protein HMG-I/HMG-Y, HMG-I(Y), High mobility group AT-hook protein 1, High mobility group protein A1, High mobility group protein RHMGA1 gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.

Molecular Weight: 11kD

Gene ID: 3159

UniProt: P17096

Pathways: Nuclear Hormone Receptor Binding, Autophagy