HRH2 antibody (AA 100-180)

Catalog No. ABIN7221570

The Rabbit Polyclonal anti-HRH2 antibody (ABIN7221570) specifically detects HRH2 in WB, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HRH2 antibody (AA 100-180) (ABIN7221570)

Target: HRH2 (Histamine Receptor H2 (HRH2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-HRH2 Antibody

Binding Specificity: AA 100-180

Purpose: Rabbit Anti-Histamine H2 Receptor Polyclonal Antibody

Specificity: Histamine H2 Receptor Polyclonal Antibody detects endogenous levels of Histamine H2 Receptor protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Histamine H2 Receptor at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HRH2

Target: HRH2 (Histamine Receptor H2 (HRH2))

Alternative Name: Histamine H2 Receptor

Background: HRH2, Histamine H2 receptor, H2R, HH2R, Gastric receptor IHistamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for HRH2.

Molecular Weight: 40kD

Gene ID: 3274

UniProt: P25021