HAT1 antibody (AA 300-380)

Catalog No. ABIN7225510

This Rabbit Polyclonal antibody specifically detects HAT1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HAT1 antibody (AA 300-380) (ABIN7225510)

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HAT1 Antibody

Binding Specificity: AA 300-380

Purpose: Rabbit Anti-HAT1 Polyclonal Antibody

Specificity: HAT1 Polyclonal Antibody detects endogenous levels of HAT1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human HAT1 at AA range: 300-380

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HAT1

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Alternative Name: HAT1

Background: HAT1, KAT1, Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1The protein encoded by HAT1 (histone acetyltransferase 1)is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for HAT1.

Molecular Weight: 49kD

Gene ID: 8520

UniProt: O14929