HDAC7 antibody

Catalog No. ABIN7215216

The Rabbit Polyclonal anti-HDAC7 antibody (ABIN7215216) specifically detects HDAC7 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HDAC7 antibody (ABIN7215216)

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HDAC7 Antibody

Purpose: Rabbit Anti-HDAC7 Polyclonal Antibody

Specificity: HDAC7 Polyclonal Antibody detects endogenous levels of HDAC7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human HDAC7 around the non-phosphorylation site of S155

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HDAC7

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Alternative Name: HDAC7

Background: HDAC7, HDAC7A, Histone deacetylase 7, HD7, Histone deacetylase 7A, HD7aHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 7 encoded by HDAC7 has sequence homology to members of the histone deacetylase family. HDAC7 is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for HDAC7.

Molecular Weight: 103kD

Gene ID: 51564

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development