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Histone H2B antibody (acLys12)

This Rabbit Polyclonal antibody specifically detects Histone H2B in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Monkey.
Catalog No. ABIN7223246

Quick Overview for Histone H2B antibody (acLys12) (ABIN7223246)

Target

See all Histone H2B Antibodies
Histone H2B

Reactivity

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Human, Mouse, Monkey

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Histone H2B antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

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    acLys12

    Purpose

    Acetyl Histone H2B (K12) Polyclonal Antibody

    Specificity

    Acetyl-Histone H2B (K12) Polyclonal Antibody detects endogenous levels of Histone H2B protein only when acetylated at K12.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    Immunogen

    Synthesized peptide derived from human Histone H2B around the acetylation site of K12 at AA range: 10-90

    Isotype

    IgG
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    Comment

    Primary Antibody

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Target

    Histone H2B

    Background

    Rabbit Anti-Acetyl Histone H2B (K12) Polyclonal Antibody,H2BFS, Histone H2B type F-S, Histone H2B.s, H2B/s,H2BFS (H2B Histone Family Member S (Pseudogene)) is a Pseudogene. Diseases associated with H2BFS include endometrial stromal sarcoma. Among its related pathways are Packaging Of Telomere Ends. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BH.,Histone H2B type F-S

    Gene ID

    54145

    UniProt

    P57053
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