HABP2 antibody (AA 270-350)

Catalog No. ABIN7212518

This Rabbit Polyclonal antibody specifically detects HABP2 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HABP2 antibody (AA 270-350) (ABIN7212518)

Target: HABP2 (Hyaluronan Binding Protein 2 (HABP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HABP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HABP2 Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-HABP2 Polyclonal Antibody

Specificity: HABP2 Polyclonal Antibody detects endogenous levels of HABP2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human HABP2 at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HABP2

Target: HABP2 (Hyaluronan Binding Protein 2 (HABP2))

Alternative Name: HABP2

Background: HABP2, HGFAL, PHBP, Hyaluronan-binding protein 2, Factor VII-activating protease, Factor seven-activating protease, FSAP, Hepatocyte growth factor activator-like protein, Plasma hyaluronan-binding proteinHABP2 encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in HABP2 are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Molecular Weight: 63kD

Gene ID: 3026

UniProt: Q14520