IGKV1-27 antibody (AA 290-370)

Catalog No. ABIN7213398

This Rabbit Polyclonal antibody specifically detects IGKV1-27 in WB, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for IGKV1-27 antibody (AA 290-370) (ABIN7213398)

Target: IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGKV1-27 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-IGKV1-27 Antibody

Binding Specificity: AA 290-370

Purpose: A20 Polyclonal Antibody

Specificity: A20 Polyclonal Antibody detects endogenous levels of A20 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human A20 at AA range: 290-370

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IGKV1-27

Target: IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))

Alternative Name: A20

Background: Rabbit Anti-A20 Polyclonal Antibody,TNFAIP3, OTUD7C, Tumor necrosis factor alpha-induced protein 3, TNF alpha-induced protein 3, OTU domain-containing protein 7C, Putative DNA-binding protein A20, Zinc finger protein A20,TNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for TNFAIP3.,Tumor necrosis factor alpha-induced protein 3

Gene ID: 7128

UniProt: P21580

Pathways: Activation of Innate immune Response