Importin 9 antibody

Catalog No. ABIN7229180

The Rabbit Polyclonal anti-Importin 9 antibody is suitable to detect Importin 9 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for Importin 9 antibody (ABIN7229180)

Target: Importin 9 (IPO9)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Importin 9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Importin 9 Antibody

Purpose: Rabbit Anti-IPO9 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IPO9 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IPO9 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Importin 9

Target: Importin 9 (IPO9)

Alternative Name: IPO9

Background: Importin-9, Imp9, Ran-binding protein 9, RanBP9IPO9 (Importin 9) is a Protein Coding gene. Diseases associated with IPO9 include Atypical Lipomatous Tumor. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.

Molecular Weight: 114kD

Gene ID: 55705

UniProt: Q96P70

Pathways: Protein targeting to Nucleus