The Rabbit Polyclonal anti-ITPKB antibody (ABIN7221920) specifically detects ITPKB in WB and ELISA.
The antibody is reactive with Human, Mouse and Rat samples.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Expiry Date
12 months
Target
ITPKB
(Inositol-Trisphosphate 3-Kinase B (ITPKB))
Alternative Name
InsP 3-kinase B
Background
ITPKB, Inositol-trisphosphate 3-kinase B, Inositol 1, 4,5-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, InsP 3-kinase BThe protein ITPKB encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.