INSRR antibody (AA 80-160)

Catalog No. ABIN7229156

The Rabbit Polyclonal anti-INSRR antibody (ABIN7229156) specifically detects INSRR in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for INSRR antibody (AA 80-160) (ABIN7229156)

Target: INSRR (Insulin Receptor-Related Receptor (INSRR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSRR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-INSRR Antibody

Binding Specificity: AA 80-160

Purpose: Rabbit Anti-INSRR Polyclonal Antibody

Specificity: The antibody detects endogenous levels of INSRR protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human INSRR protein at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for INSRR

Target: INSRR (Insulin Receptor-Related Receptor (INSRR))

Alternative Name: INSRR

Background: IR-related receptorINSRR (Insulin Receptor Related Receptor) is a Protein Coding gene. Diseases associated with INSRR include Regular Astigmatism and Podoconiosis. Among its related pathways are Akt Signaling and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is IGF1R. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH . Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Molecular Weight: 142kD

Gene ID: 3645

UniProt: P14616

Pathways: RTK Signaling