ITGB1 antibody (pThr789)

Catalog No. ABIN7221890

This Rabbit Polyclonal antibody specifically detects ITGB1 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ITGB1 antibody (pThr789) (ABIN7221890)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ITGB1 Antibody

Binding Specificity: pThr789

Purpose: Integrin β1 (phospho Thr789) Polyclonal Antibody

Specificity: Phospho-Integrin β1 (T789) Polyclonal Antibody detects endogenous levels of Integrin β1 protein only when phosphorylated at T789.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Integrin beta1 Phospho-Thr789

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: Integrin beta1

Background: Rabbit Anti-Integrin β1 (phospho Thr789) Polyclonal Antibody,ITGB1, FNRB, MDF2, MSK12, Integrin beta-1, Fibronectin receptor subunit beta, VLA-4 subunit beta, CD antigen CD29,Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.,Integrin beta-1

Molecular Weight: observerd band 90kDa

Gene ID: 3688

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome